Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.

Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.

Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.

Lipase Treatment of Dietary Krill Oil, but Not Fish Oil, Enables Enrichment of Brain Eicosapentaenoic Acid and Docosahexaenoic Acid.

Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice

Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye

Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: lysophosphatidylcholine is more efficient than either phosphatidylcholine or triacylglycerol

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain

Dietary lysophosphatidylcholine-EPA enriches both EPA and DHA in the brain: potential treatment for depression

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome

Insights into major facilitator superfamily domain-contaning protein-2a (Mfsd2a) in physiology and pathophysiology. What do we know so far?

Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy

Mfsd2a is critical for the formation and function of the blood-brain barrier

Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism

The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8 + Memory T Cell Maintenance and Secondary Response to Infection

Homozygous mutation in MFSD2A, encoding a lysolipid transporter for docosahexanoic acid, is associated with microcephaly and hypomyelination

Lysophosphatidylcholine as a preferred carrier form of docosahexaenoic acid to the brain

Preferential incorporation of sn-2 lysoPC DHA over unesterified DHA in the young rat brain

Plasma BDNF is a more reliable biomarker than erythrocyte omega-3 index for the omega-3 fatty acid enrichment of brain

Perspective: The Potential Role of Circulating Lysophosphatidylcholine in Neuroprotection against Alzheimer Disease

Omega-3 PUFA metabolism and brain modifications during aging

Carriers of an apolipoprotein E epsilon 4 allele are more vulnerable to a dietary deficiency in omega-3 fatty acids and cognitive decline

Docosahexaenoic acid prevents cognitive deficits in human apolipoprotein E epsilon 4-targeted replacement mice

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation

Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases

Mfsd2a-based pharmacological strategies for drug delivery across the blood-brain barrier

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid

Blood-brain barrier: a dual life of MFSD2A?

Docosahexaenoic acid (DHA) and the developing central nervous system (CNS) - Implications for dietary recommendations

Lipidomics reveals a remarkable diversity of lipids in human plasma

DHA deficiency and prefrontal cortex neuropathology in recurrent affective disorders

A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2

The aging human orbitofrontal cortex: decreasing polyunsaturated fatty acid composition and associated increases in lipogenic gene expression and stearoyl-CoA desaturase activity

Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors

The role of essential fatty acids in development

Preferential transfer of 2-docosahexaenoyl-1-lysophosphatidylcholine through an in vitro blood-brain barrier over unesterified docosahexaenoic acid

Characterization of plasma unsaturated lysophosphatidylcholines in human and rat

The uptake and metabolism of plasma lysophosphatidylcholine in vivo by the brain of squirrel monkeys

Transport of lysolecithin by albumin in human and rat plasma

Metabolism of glycerolipids. 2. The enzymatic acylation of lysolecithin

Maternal DHA and the development of attention in infancy and toddlerhood